DERMORPHIN 10mg
DERMORPHIN 10mg
High-Purity Research Peptide | For Laboratory Research Only
Dermorphin is a naturally occurring opioid peptide originally identified in the skin of Phyllomedusa frogs. It is a seven-amino-acid peptide with the sequence Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂ and is notable for containing a D-amino acid, an unusual feature among naturally produced animal peptides. (PubMed)
What Makes Dermorphin Interesting?
Dermorphin has attracted significant scientific interest because of its high affinity and selectivity for μ-opioid (mu-opioid) receptors. These receptors are involved in the central nervous system’s regulation of nociception and opioid signaling. (PubMed)
Key Research Areas
μ-Opioid Receptor Activity
Dermorphin acts primarily as a potent μ-opioid receptor agonist, making it useful experimentally for investigating opioid-receptor activation, selectivity and signaling pathways.
Nociception & Analgesia Research
Preclinical studies have demonstrated strong antinociceptive activity from dermorphin and related analogues. This has made the dermorphin family an important subject in experimental pain and analgesic research. (PubMed)
Central Nervous System Research
Researchers have investigated dermorphin and its analogues to better understand central opioid pathways, receptor pharmacology and the relationship between peptide structure and biological activity.
Receptor Selectivity
One of dermorphin’s most notable characteristics is its preference for μ-opioid receptors compared with other opioid-receptor subtypes. Structural modifications of dermorphin have therefore been extensively studied to determine how individual amino acids influence receptor affinity and selectivity. (PubMed)
Peptide & Drug-Development Research
Dermorphin provides an interesting molecular framework for studying the development of highly selective opioid-receptor ligands. Numerous dermorphin-derived analogues have been synthesized and evaluated experimentally. (PubMed)
Product Specifications
Product: Dermorphin
Quantity: 10mg
Form: Lyophilized peptide
Testing: HPLC purity verification where supported by the applicable batch COA
Storage: Store refrigerated according to the product label and batch documentation
Classification: Research Use Only (RUO)
Important Research Notice
FOR RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION.
Dermorphin is a potent opioid-receptor agonist and should not be presented as a dietary supplement, wellness product, pain treatment or medication. This product is intended exclusively for legitimate laboratory and analytical research.
It has not been approved by Health Canada for human therapeutic use. No claims are made regarding safety, effectiveness, diagnosis, treatment, cure or prevention of any disease or medical condition.
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